Patents
-
Four patents on molecular structure and medical use of F2i, a first-in-class FRS2 inhibitor – Small molecule inhibitors of the frs2-fgfr interaction
-
Patent on novel 3D tumouroid plate and drug discovery platform ACINDA – Multiwell, microscope-compatible device for high-throughput analysis of cell invasion
Publications
-
Repression of Aurora kinase B prevents growth and tissue invasion in medulloblastoma
-
Discovery of a small molecule ligand of FRS2 that inhibits invasion and tumour growth
-
Crosstalk between SHH and FGFR Signaling Pathways Controls Tissue Invasion in Medulloblastoma
-
Synthetic Activators of Cell Migration Designed by Constructive Machine Learning
-
Identification of synthetic activators of cancer cell migration by hybrid deep learning
-
TGF-b Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma
-
Investigation of brain tissue infiltration by medulloblastoma cells in an ex vivo model
-
Computer-assisted quantification of motile and invasive capabilities of cancer cells